Zinc metabolism and dibutyl phthalate-induced testicular atrophy in the rat.

نویسندگان

  • B R Cater
  • M W Cook
  • S D Gangolli
چکیده

Kuriyama, Y . (1972) J. Biol. Chem. 247,2979-2988 Nilsson, R., Peterson, E. & Dallner, G. (1973) J. CeN Biol. 56, 762-776 Pogell, B. M. & Leloir, L. F. (1961) J . Biol. Chem. 236, 293-298 Vessey, D. A. 8c Zakim, D. (1974) Biochem. J. 139,243-249 Winsnes, A. (1969) Biochim. Biophys. Acta 191,279-291 Winsnes, A. (1971) Biochim. Biophys. Acta 242, 549-559 Winsnes, A. (1972a) Biochim. Biophys. Acta 284,394-405 Winsnes, A. (19726) Biochim. Biophys. Acta 289.88-96 Zakirn, D. & Vessey, D. A. (1974) Biochem. Soc. Trans. 2, 1165-1167

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Testicular effects of phthalate esters.

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Aspects of the testicular toxicity of phthalate esters.

Di(2-ethylhexyl) phthalate (DEHP) produced seminiferous tubular atrophy and reductions in seminal vesicle and prostate weight in 4-week-old, but not in 15-week-old rats. Di-n-pentyl phthalate (DPP) did produce atrophy in the older rats but this developed more slowly than in young animals. Coadministration of testosterone or gonadotrophins did not protect against phthalate-induced testicular tox...

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The orl rat with inherited cryptorchidism has increased susceptibility to the testicular effects of in utero dibutyl phthalate exposure.

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عنوان ژورنال:
  • Biochemical Society transactions

دوره 4 4  شماره 

صفحات  -

تاریخ انتشار 1976